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Admin02.07.2021

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Without addition of EGF, [ 3H]thymidine incorporation as a measure of cell proliferation is not significantly different for either CTSL genotype.

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Admin17.07.2021

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Admin27.07.2021

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These could be increased translation efficiency or, more likely, a prolonged half-life of the receptor.

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Admin13.08.2021

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409

Admin03.09.2021

The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling

Paraffin sections were stained in haematoxylin and eosin HE or by immunohistochemistry for the proliferation marker Ki67 Ki67, brown nuclear staining and the differentiation markers cytokeratin 10 K10, brown staining and transglutaminase TG, brown staining.

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Admin02.09.2021

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Keratinocytes and fibroblasts are the prominent epidermal and dermal cell types, respectively.

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Admin24.06.2021

The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling

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Admin21.06.2021

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Standard procedures were followed to generate transgenic mice by microinjection of the purified expression cassette into the pronuclei of one-cell-stage embryos and their subsequent re-transfer into the oviducts of pseudopregnant recipient females.

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67010

Admin24.07.2021

The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling

Paraffin sections were stained in haematoxylin and eosin HE or by immunohistochemistry for the proliferation marker Ki67 Ki67, brown nuclear staining and the differentiation markers cytokeratin 10 K10, brown staining and transglutaminase TG, brown staining.

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9109

Admin09.08.2021

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B Degraded 125I-EGF in the medium.

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Admin07.08.2021

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Our results obtained with this system show that CTSL-deficiency in dermal fibroblasts does neither affect the proliferation nor the differentiation of keratinocytes, which further excludes a CTSL-dependent role of dermal fibroblasts in epidermal proliferation.

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Admin17.07.2021

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Microscopy was performed with an Axioplan microscope Zeiss, Stuttgart, Germany and digital images were obtained with an Axiocam camera Zeiss.

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