Cristina Fenollar nackt sorted by
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Admin29.08.2021

Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins

TM helices in the model are indicated with gray rectangles.
8808
Admin20.06.2021

Arielle Kebbel Nude, Fappening, Sexy Photos, Uncensored

TMC1 secondary structure prediction ssp is shown at the top of the alignment and secondary structure information extracted from nhTMEM16 and mTMEM116A structures dssp1 and dssp2, respectively is included below the corresponding sequences.
501
Admin18.08.2021

Arielle Kebbel Nude, Fappening, Sexy Photos, Uncensored

DOI: The hair cell mechanotransduction MET channel complex is essential for hearing, yet it's molecular identity and structure remain elusive.
6507
Admin16.08.2021

Lorenza Izzo Nude, Fappening, Sexy Photos, Uncensored

Representation of mTMC1 topology revealing intracellular N- and C- terminal domains and 10 transmembrane TM helices.
1800
Admin22.07.2021

Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins

Three predicted extracellular N-glycosylation sites located in the extracellular TM5-TM6 loop are shown as light-green rhombus.
1701
Admin21.08.2021

Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins

The molecular surface was calculated based on van der Waals radii with a probe radius of 1.
7104
Admin14.07.2021

Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins

MD simulations reveal that the intermolecular interactions preferentially occur between specific PIP2 phosphate groups and hPLD2 residues; the most strongly interacting residues are arginine at the pbox consensus sequence PX and pleckstrin homology PH domain.
4707
Admin14.06.2021

PLD2

A Confocal images of the same hair cells shown in Figure 8A at the stereocilia level showing stereocilia dextran labeling magenta in the absence and presence of BAPTA or MET channel blockers.
8805
Admin08.07.2021

PLD2

Model 1 reveals a wide-open cavity exposed to the membrane environment, while the TM4 helix is repositioned in model 2 to partially close the cavity red towards the EC side.
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